Information for Cancer Patients & Healthcare Providers
SafeVite is a daily multivitamin formulated by our cancer experts who have analyzed a comprehensive number of peer reviewed published articles and research studies. (see references on this website as a partial listing of the articles and studies) Safevite is an affordable daily multivitamin, that contains specific vitamins while avoiding or limiting doses of other vitamins. We believe SafeVite addresses the following: Certain vitamins are best to avoid during radiation therapy or chemotherapy and the majority of these same vitamins haven’t been proven to be beneficial to the cancer patient or survivor even when not on cancer treatments. This may even extends to targeted treatments and or immunotherapy.
Additionally our references suggest that certain vitamin types are clearly deficient in many cancers and may lead to increased risk of developing certain cancers or even dying from certain cancers. Certain vitamin levels are elevated in some cancers, such as calcium in patients with bone metastasis or with increased PTHrp, and therefore best to simply avoid. On the other hand, when taking a biphosphonate or RANK ligand, you’ll have to prescribe calcium with vitamin D as recommended unless contraindicated. Certain vitamins address cancer treatment related toxicities such as bone fracture risk, neuropathy or alopecia, hair thinning (to name just a couple of the many known treatment related toxicities).
As mention above, certain vitamins appear to prevent or reduce the risk of some cancers and are more appropriate given their other benefits. This includes Vitamin B6 for example which is reasonable when neuropathy is present. Although multivitamins should be used at or near the recommended daily allowances, though when it comes to cancer, treatments or treatment toxicities; a specific vitamin dose should be increased while other doses best limited or a vitamin even avoided. So the question exists; are there peer reviewed published articles and research studies that conclude which vitamins are beneficial and which are best limited or therefore avoided?
The answer is YES. There are other reasons to have an interest in vitamins. The use of vitamins is extremely prevalent in our patient population and these patients expect that in addition to directing their cancer treatments and surgery, we should convey and offer what is most reasonable. Otherwise they are on their own when it comes to often expensive supplements and alternative choices. Fortunately it’s a fact that despite being too busy while addressing our patients many needs, we can offer an affordable appropriate vitamin. Recommend SafeVite as your preferred multivitamin and at least keep this part simple when supporting their fight against cancer.
SafeVite reference guide
Vitamins and Cancer Patients
- 1. Dietary intake of one-carbon metabolism-related nutrients and pancreatic cancer risk: The Singapore Chinese Health Study
- 2. Dietary Vitamin B6 Intake and the Risk of Colorectal Cancer
- 3. Clinical trials of vitamin and mineral supplements for cancer prevention
- 4. “What’s the Harm?”: Alternative Therapies and Supplements Can Impede Cancer Care
- 5. Know the Difference Between Fat- and Water-Soluble Nutrients
- 6. The nutritional risk in oncology: a study of 1,453 cancer outpatients.
- 7. Peripheral Neuropathy Due to Vitamin Deficiency, Toxins, and Medications
- 8. A double-blind placebo-controlled randomized study of Chinese herbal medicine as complementary therapy for reduction of chemotherapy-induced toxicity
- 9. Cancer: In Depth
Vitamin D (as cholecalciferol)
- 1. The Role of Vitamin D in Cancer Prevention
- 2. Association between vitamin D and risk of colorectal cancer: a systematic review of prospective studies.
- 3. Prostate cancer risk and prediagnostic serum 25-hydroxyvitamin D levels (Finland).
- 4. Vitamin D and breast cancer risk: the NHANES I Epidemiologic follow-up study, 1971-1975 to 1992. National Health and Nutrition Examination Survey.
- 5. Serum 25-Hydroxyvitamin D Concentrations ≥40 ng/ml Are Associated with >65% Lower Cancer Risk: Pooled Analysis of Randomized Trial and Prospective Cohort Study
- 6. Hypercalcemia (Elevated Calcium Levels)
Thiamin (as thiamin HCI)
Riboflavin
- 1. Anti-angiogenic potential of CoenzymeQ10, riboflavin and niacin in breast cancer patients undergoing tamoxifen therapy.
- 2. Riboflavin Arrests Cisplatin-Induced Neurotoxicity by Ameliorating Cellular Damage in Dorsal Root Ganglion Cells
- 3. Riboflavin
Niacin
- 1. Anti-angiogenic potential of CoenzymeQ10, riboflavin and niacin in breast cancer patients undergoing tamoxifen therapy.
- 2. Niacin And Niacinamide (Vitamin B3)
- 3. Niacin and carcinogenesis.
- 4. Niacin status and treatment-related leukemogenesis
- 5. Riboflavin Arrests Cisplatin-Induced Neurotoxicity by Ameliorating Cellular Damage in Dorsal Root Ganglion Cells
- 6. Clinical Investigation in Effect of Riboflavin Sodium Phosphate on Prevention and Treatment for Patients with Radiotherapy Related Esophagitis
Vitamin B6 (as pyridoxine HCI)
- 1. Vitamins B6 and cancer.
- 2. B vitamin intakes and incidence of colorectal cancer: results from the Women’s Health Initiative Observational Study cohort.
- 3. Peripheral Neuropathy and B Vitamins
- 4. High circulating vitamin B6 linked to lower risk of ER+/PR+ breast cancer
Vitamin B12 (as cyanocobalamin)
- 1. Homocysteine and vitamin B12 status relate to bone turnover markers, broadband ultrasound attenuation, and fractures in healthy elderly people.
- 2. Vitamin B12 deficiency and breast cancer.
- 3. A prospective study on folate, B12, and pyridoxal 5′-phosphate (B6) and breast cancer.
- 4. Vitamin B12 Deficiency
Biotin
Pantothenic acid (as D-calcium pantothenate)
Magnesium (as magnesium oxide)
- 1. Hypomagnesemia in critically ill cancer patients:
- 2. Calcium, Magnesium, and Colorectal Cancer – NCBI – NIH
- 3. Magnesium concentration variations during carcinogenesis
Copper (as copper gluconate)
- 1. Copper deficiency and sideroblastic anemia associated with zinc ingestion.
- 2. Copper and Zinc, Biological Role and Significance of Copper/Zinc Imbalance
- 3. Zinc-induced copper deficiency: a report of three cases initially recognized on bone marrow examination.
- 4. Image Diagnosis: Zinc-Induced Copper Deficiency Causing Pancytopenia Recognized on Bone Marrow Examination
Chromium (as chromium nicotinate glycinate chelate)
Molybdenum (as sodium molybdate)
Articles referencing vitamins to avoid as a Cancer Patient
- 1. Vitamin E and the risk of prostate cancer: the Selenium and Vitamin E Cancer Prevention Trial (SELECT).
- 2. Amino Acid Profiling of Zinc Resistant Prostate Cancer Cell Lines: Associations With Cancer Progression
- 3. Effects of a combination of beta carotene and vitamin A on lung cancer and cardiovascular disease.
- 4. Should supplemental antioxidant administration be avoided during chemotherapy and radiation therapy?
- 5. The effect of vitamin E and beta carotene on the incidence of lung cancer and other cancers in male smokers.
- 6. Cancer-related hypercalcemia